Stanford Database Library of American Journal of Applied Science and Technology

Vol. 6 No. 03 (2026)
Articles

Molecular Mechanisms of DNA Damage and Their Role in The Development of Carcinogenesis

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  • Rasulova Y.Z.,
  • Xidirqulov J.J.
Rasulova Y.Z.
Assistant of Bukhara State Medical Institute, Uzbekistan
Xidirqulov J.J.
Student of Bukhara State Medical Institute, Uzbekistan

Published 2026-03-30

Keywords

  • DNA damage,
  • Carcinogenesis

How to Cite

Rasulova Y.Z., & Xidirqulov J.J. (2026). Molecular Mechanisms of DNA Damage and Their Role in The Development of Carcinogenesis. Stanford Database Library of American Journal of Applied Science and Technology, 6(03), 111–114. Retrieved from http://oscarpubhouse.com/index.php/sdlajast/article/view/1657

Copyright (c) 2026 Rasulova Y.Z., Xidirqulov J.J.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

It is well-established that external factors inevitably exert an influence at the level of human molecular mechanisms. These factors induce mutations and trigger the activation of oncogenes. Proto-oncogenes (growth factors, apoptosis inhibitors) and oncogenes (nuclear and Ras genes) are considered the fundamental basis of carcinogenesis. Tumors lead to severe clinical outcomes, such as astrocytoma, glioblastoma, as well as gastric and lung cancers. This research was conducted based on clinical data and biochemical analysis methods from the past six years. In conclusion, the study of biomarkers serves as a critical foundation for the early detection and diagnosis of neoplastic and genetic diseases.

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